Elisabetta Manduchi


Address
Computational Genetics Laboratory
University of Pennsylvania
D 201 Richards Bldg.
3700 Hamilton Walk
Philadelphia, PA 19104

Contact
phone: (215) 573-4408
email: manduchi@upenn.edu



Experience
Education
Research interests
Publications


Experience


Education


Research interests

I am a Bioinformatics Scientist, with extensive experience in analysis and management of high-throughput biological data, including development of methods, algorithms, computational tools, functional genomics databases and web resources. I am a former member of CBIL (UPenn), where I have been involved in several projects including: Beta Cell Genomics (Project Manager), RAD and GUS, PaGE, and Significance Testing for Direct  Identity-by-descent mapping (STeDI). As part of CBIL, I have collaborated with many investigators both within and outside of the University of Pennylvania, including a long-term collaboration with Professor Peter Davies' group at UPenn on analyses of high-throughput datasets relative to Cardiovascular Biology. I have also collaborated with Dr. Greg Grant's bioinformatics group at ITMAT (UPenn) on methods and code to pre-process and analyze RNA-Seq data. In 2015 I have joined the Computational Genetics Laboratory in the Institute for Biomedical Informatics at UPenn where I work on approaches for identifying genetic and genomic biomarkers associated with human health and disease, embracing the complexity of the genotype-to-phenotype mapping relationship due to phenomena such as epistasis. In addition, I spend part of my time working within the Spatial and Functional Genomics Initiative (SFGI) at The Children's Hospital of Philadelphia (CHOP), led by Professors Struan Grant, Gerd Blobel and Andrew Wells. As part of this initiative I work on analysis of Chromosome Conformation Capture high-throuput data.


Publications

Mathematics

Computational Biology/Bioinformatics